Tan Shi Ying, Telisinghe Pemasiri Upali, Keasberry Justin Fook Siong
{"title":"Painless Cervical Lymphadenopathy in an Elderly Patient - A Rare Case of Rosai-Dorfman Disease and Hodgkin's Lymphoma","authors":"Tan Shi Ying, Telisinghe Pemasiri Upali, Keasberry Justin Fook Siong","doi":"10.23937/2378-3656/1410371","DOIUrl":null,"url":null,"abstract":"Rosai-Dorfman disease is a rare, benign disease presenting with extensive lymphadenopathy. In this case, an 81-yearold gentleman with previous pulmonary tuberculosis, presented with painless cervical lymphadenopathy associated with generalized weakness, loss of appetite, and cough. The causes of cervical lymphadenopathy in elderly are comprehensive; hence thorough history taking, examination, and appropriate investigations are vital in diagnosing diseases. If blood investigations and imaging are inconclusive, a lymph node biopsy is recommended. He was later diagnosed with Rosai-Dorfman disease associated with Hodgkin’s lymphoma and dexamethasone treatment was initiated. Concomitant diagnoses are rare, but should not disregarded. Regular monitoring is required as immune dysregulation may exacerbate quiescent, treated pulmonary tuberculosis.","PeriodicalId":10450,"journal":{"name":"Clinical Medical Reviews and Case Reports","volume":"4 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medical Reviews and Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2378-3656/1410371","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Rosai-Dorfman disease is a rare, benign disease presenting with extensive lymphadenopathy. In this case, an 81-yearold gentleman with previous pulmonary tuberculosis, presented with painless cervical lymphadenopathy associated with generalized weakness, loss of appetite, and cough. The causes of cervical lymphadenopathy in elderly are comprehensive; hence thorough history taking, examination, and appropriate investigations are vital in diagnosing diseases. If blood investigations and imaging are inconclusive, a lymph node biopsy is recommended. He was later diagnosed with Rosai-Dorfman disease associated with Hodgkin’s lymphoma and dexamethasone treatment was initiated. Concomitant diagnoses are rare, but should not disregarded. Regular monitoring is required as immune dysregulation may exacerbate quiescent, treated pulmonary tuberculosis.