Clinical significance of monocyte and large platelet for pulmonary embolism in patients with acute exacerbation of chronic obstructive pulmonary disease

Abstract

Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) can lead to a sharp deterioration of respiratory function, and the most chronic obstructive pulmonary disease (COPD)-associated death occurs in AECOPD.The prevalence of pulmonary embolism is high in COPD patients, especially in AECOPD patients.Pulmonary embolism and AECOPD have similar clinical symptoms.And it is difficult to distinguish them by symptoms, signs and simple laboratory tests, which leads to the excessive use of computer tomography pulmonary angiography.In recent years, many researchers have found that monocyte, platelet, especially large platelet, are evidently related to intravascular and extravascular inflammatory reaction and thrombogenesis. Key words: Acute exacerbation of chronic obstructive pulmonary disease; Pulmonary embolism; Monocyte; Large platelet