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Abstract

Hypothesis / aims of study Although overexpression of prostaglandin E2 (PGE2) in the urinary bladder of animal experimental models with bladder outlet obstruction (BOO) is involved in the micturition reflex through activation of c-fibers, there are few reports on the correlation between PGE2 in the human bladder, BOO, and reactivation of c-fibers. In the present study, we evaluated whether PGE2 in the bladder correlated with BOO and reactivation of c-fibers.