Phytochemical screening and antimicrobial activities of leaf extracts of Mucuna pruriens

Journal of Pharmaceutical and Allied Sciences Pub Date : 2019-12-18 DOI:10.4314/JOPHAS.V16I4

O. Ushie, V. Okpashi, T. Azuaga, S. Iyen, E. Aikhoje, J. I. Lajaka

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引用次数: 1

Abstract

The aim of this study is to carry out phytochemical screening of the methanol, n-hexane and ethyl acetate leaf extracts of the plant Mucuna pruriens and to evaluate their antimicrobial activities. The crude extracts were tested on three bacterial species; Klebsiella aerogenes, E coli and Pseudomonas aeruginosa and two fungal isolates – Candida albicans and Aspergillus niger . The results revealed the presence for steroids, terpenes, alkaloids, saponins, tannins, and flavonoids in the extracts. Almost all the extracts inhibited Klebsiella aerogenes , Escherichia coli , and Pseudomonas aeruginosa . The implication is that these extracts can be used to cure diseases associated with the tested organisms. Methanol extract did not inhibit growth of Aspergillus niger but demonstrated high activity against Candida albicans . The result implies that the plant can actually be used to cure diseases associated those organisms such as diarrhea, stomach cramps, and nausea. Keywords: Phytochemical screening, Mucuna pruriens, antimicrobial studies, leaf extracts Journal of Pharmaceutical and Allied Sciences, Vol. 16 No.4 (2019)

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麻豆叶提取物的植物化学筛选及抑菌活性研究

本研究的目的是对麻豆叶中甲醇、正己烷和乙酸乙酯提取物进行植物化学筛选，并评价其抑菌活性。粗提物对3种细菌进行了检测;产气克雷伯氏菌，大肠杆菌和铜绿假单胞菌以及两种真菌分离株-白色念珠菌和黑曲霉。结果显示，提取物中存在类固醇、萜烯、生物碱、皂苷、单宁和黄酮类化合物。几乎所有提取物对产气克雷伯菌、大肠杆菌和铜绿假单胞菌均有抑制作用。这意味着这些提取物可以用来治疗与被测试生物相关的疾病。甲醇提取物对黑曲霉的生长没有抑制作用，但对白色念珠菌有较高的抑制作用。这一结果表明，这种植物实际上可以用来治疗与这些微生物有关的疾病，如腹泻、胃痉挛和恶心。关键词:植物化学筛选;毛粘虫;抗菌研究;

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Journal of Pharmaceutical and Allied Sciences

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