Therapeutic potential of Bee gomogenat against testicular damage in a streptozotocin- induced type I diabetic mouse model

Abstract

Diabetes Mellitus (DM) is a metabolic disorder that has serious effects for male fertility. Additionally, DM mediates impairment of spermatogenesis; decrease in sperm count, viability, and motility; and apoptosis in both somatic and germ cells. This study aimed to investigate the dietary effect of bee gomogenat (BG) supplementation on the architecture of testis in a mouse model of streptozotocin (STZ)-induced type 1 diabetes (TID). Mice were allocated to three different groups: control non-diabetic, YAP+ Leydig cells and the testosterone level. Furthermore, Treatment of diabetic