{"title":"Three-dimensional motion of a nanoparticle on the cell membrane observed by non-interferometric widefield optical profilometry","authors":"Chau-Hwang Lee, Chun-Chieh Wang, Chia-Wei Lee, Chia-Yun Huang, Jiunn-Yuan Lin, P. Wei","doi":"10.1109/CLEO.2008.4551890","DOIUrl":null,"url":null,"abstract":"We directly observe three-dimensional motion of a gold nanoparticle on the membrane of a living cell by using non-interferometric widefield optical profilometry. We identify the occurrence of particle internalization and actin aggregation which indicates endocytosis.","PeriodicalId":6382,"journal":{"name":"2008 Conference on Lasers and Electro-Optics and 2008 Conference on Quantum Electronics and Laser Science","volume":"25 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2008-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2008 Conference on Lasers and Electro-Optics and 2008 Conference on Quantum Electronics and Laser Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/CLEO.2008.4551890","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We directly observe three-dimensional motion of a gold nanoparticle on the membrane of a living cell by using non-interferometric widefield optical profilometry. We identify the occurrence of particle internalization and actin aggregation which indicates endocytosis.