Equine Motor Neuron Disease: A Review of Clinical and Experimental Studies

Abstract

Epidemiological, pathological, laboratory, and experimental studies all support the hypothesis that equine motor neuron disease is an oxidative disorder associated with prolonged vitamin E deficiency. The role that pro-oxidants play in the disease has not been determined. All horses without access to green forage and/or with low plasma vitamin E levels should be supplemented with vitamin E.