Management of lower limbs leiomyosarcoma: A case report

Cuenca-Gonzalez Concepcion, Berzal Cantalejo Maria Fernanda, Herranz-Torrubiano Ana Maria, Lucia Vaamonde Lorenzo
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Abstract

We report the case of a woman referred to our rehabilitation department who presented a soft tissue tumour, a proximal third tibia leiomyosarcoma. It’s analyzed how the diagnosis was made, the treatment for tumour and its sequelae and the follow up period, by doing an update of the scientific evidence in this tumour management. This tumour is a subtype in soft tissue sarcomas. These are rare tumours that arise mostly from mesenchymal tissues and leiomyosarcoma is the fourth in frequency (12%). Although they can appear in any location, 40% cases have their origin typically in extremities. Sarcomas in extremities are characterized by a painless mass, incidentally discovered by the patient, the doctor or by performing an ultrasound. Conservative surgery is considered the main treatment for this soft tissue sarcoma, avoiding radical surgeries which don’t achieve survival results. Radiotherapy and adjuvant chemotherapy are used both with surgery to prevent local recurrence and metastases. Pathology and imaging tests (ultrasounds, CT and MRI) will be fundamental for the staging, for therapeutic decisions to be made and for monitoring possible local recurrences or regional or systemic metastases. Correspondence to: Cuenca-González Concepción, Universidad Complutense, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Physical Medicine and Rehabilitation Service, Hospital Clínico San Carlos, Madrid, Spain, Tel: +34 91 330 36 03; E-mail: cuchacuenca@gmail.com
下肢平滑肌肉瘤的治疗1例
我们报告的情况下,一名妇女转介到我们的康复部门谁提出了软组织肿瘤,近第三胫骨平滑肌肉瘤。它分析了如何做出诊断,肿瘤的治疗及其后遗症和随访期,通过更新肿瘤管理的科学证据。这个肿瘤是软组织肉瘤的一个亚型。这是一种罕见的肿瘤,主要发生在间质组织中,平滑肌肉瘤的发病率排名第四(12%)。尽管它们可以出现在任何部位,但40%的病例通常起源于四肢。四肢肉瘤的特点是无痛肿块,由病人、医生偶然发现或通过超声检查发现。保守手术被认为是这种软组织肉瘤的主要治疗方法,避免根治性手术,根治性手术不能达到生存效果。放疗和辅助化疗与手术同时使用,以防止局部复发和转移。病理和影像学检查(超声、CT和MRI)将是分期、治疗决策和监测可能的局部复发或区域或全身转移的基础。通信:Cuenca-González Concepción,康普顿斯大学医学院,物理医学和康复系,物理医学和康复服务,Clínico圣卡洛斯医院,马德里,西班牙,电话:+34 91 330 36 03;电子邮件:cuchacuenca@gmail.com
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