{"title":"Malaria Parasite Infection and Chloroquine-Induced Pruritus: The Role of Opioid-Peptides","authors":"O. Adeyemi, E. Iwalewa, M. Akanmu, O. Ukponmwan","doi":"10.4314/WAJPDR.V22I1.14765","DOIUrl":null,"url":null,"abstract":"Pruritus or itch is associated with malaria infection and/or chloroquine chemotherapy. This study examined the relationship between parasitaemia and chloroquine (CQ) on body scratching (BS) in healthy (un-infected) and malaria-infected rats. The malaria parasite induced a significant (p Keywords : Rats, parasitaemia, chloroquine, opioids, antihistamine, naltrexone West African Journal of Pharmacology and Drug Research Vol. 22/23 2007: pp. 31-38","PeriodicalId":23624,"journal":{"name":"West African journal of pharmacology and drug research","volume":"32 1","pages":"31-38"},"PeriodicalIF":0.0000,"publicationDate":"2008-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"West African journal of pharmacology and drug research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/WAJPDR.V22I1.14765","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Pruritus or itch is associated with malaria infection and/or chloroquine chemotherapy. This study examined the relationship between parasitaemia and chloroquine (CQ) on body scratching (BS) in healthy (un-infected) and malaria-infected rats. The malaria parasite induced a significant (p Keywords : Rats, parasitaemia, chloroquine, opioids, antihistamine, naltrexone West African Journal of Pharmacology and Drug Research Vol. 22/23 2007: pp. 31-38