Malaria Parasite Infection and Chloroquine-Induced Pruritus: The Role of Opioid-Peptides

O. Adeyemi, E. Iwalewa, M. Akanmu, O. Ukponmwan
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Abstract

Pruritus or itch is associated with malaria infection and/or chloroquine chemotherapy. This study examined the relationship between parasitaemia and chloroquine (CQ) on body scratching (BS) in healthy (un-infected) and malaria-infected rats. The malaria parasite induced a significant (p Keywords : Rats, parasitaemia, chloroquine, opioids, antihistamine, naltrexone West African Journal of Pharmacology and Drug Research Vol. 22/23 2007: pp. 31-38
疟疾寄生虫感染与氯喹致瘙痒:阿片肽的作用
瘙痒或发痒与疟疾感染和/或氯喹化疗有关。本研究探讨了寄生虫血症与氯喹(CQ)对健康(未感染)和疟疾感染大鼠身体抓伤(BS)的影响。关键词:大鼠,寄生虫血症,氯喹,阿片类药物,抗组胺药,纳曲酮。西非药理学与药物研究Vol 22/23 2007: pp. 31-38
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