The ketogenic diet: a co-therapy in the treatment of mood disorders and obesity - a case report

Current Problems of Psychiatry Pub Date : 2021-03-01 DOI:10.2478/cpp-2021-0002

Agata Pieklik, Martyna Pawlaczyk, J. Rog, H. Karakuła-Juchnowicz

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引用次数: 1

Abstract

Abstract Introduction: There has been a growing interest in the ketogenic diet (KD) due to its suggested therapeutic potential to support numerous chronic diseases. KD is characterized by high amounts of fats and a reduced amount of carbohydrates and protein intake. During following the nutrition protocol, ketones are synthesised, which are the primary source of energy. The elevated concentration of ketones in blood serum inhibits hunger, what leads to reduced body weight. Some authors suggest KD has antidepressant potential and could stabilise mood by affecting neurotransmitters homeostasis in the central nervous system. Material and methods: The aim of the study was to assess the effect of KD on body weight reduction and improvement of mood in the patients with mood disorder diagnosis. To interpret the results of nutritional intervention, the laboratory parameters and structuralised scales and questionnaires were used. Results: After following 4-week therapy, the reduction of body weight, correction of some laboratory measurements and reduction in mood symptoms were noticed. Conclusions: The ketogenic diet affects the anthropometric measurements. However, a variety of simultaneous therapeutic approaches makes impossible determination of the effect on depressive symptoms.

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生酮饮食:一种治疗情绪障碍和肥胖的联合疗法——一例报告

摘要:由于生酮饮食(KD)具有支持多种慢性疾病的治疗潜力，人们对其越来越感兴趣。KD的特点是脂肪含量高，碳水化合物和蛋白质摄入量少。在遵循营养方案的过程中，酮被合成，这是能量的主要来源。血清中酮的浓度升高会抑制饥饿感，从而导致体重减轻。一些作者认为，KD具有抗抑郁的潜力，可以通过影响中枢神经系统的神经递质稳态来稳定情绪。材料与方法:本研究的目的是评估KD对诊断为情绪障碍患者的体重减轻和情绪改善的影响。为了解释营养干预的结果，使用了实验室参数、结构化量表和问卷。结果:经过4周的治疗，患者体重减轻，部分实验室测量指标纠正，情绪症状减轻。结论:生酮饮食影响人体测量。然而，多种同时治疗的方法使得不可能确定对抑郁症状的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Problems of Psychiatry

自引率

0.00%

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审稿时长

15 weeks

期刊介绍： The quarterly Current Problems of Psychiatry is a continuation of the volume "Research on Schizophrenia" and is addressed to a wide group of psychiatrists and clinical psychologists. The quarterly is a reviewed scientific journal of international scope, publishing original papers, review papers, case studies, conference reports, letters to the editor and book reviews. The aim of the "Current Problems of Psychiatry" is providing a wide audience with scientific works, representing a significant contribution to the development of psychiatry and clinical psychology. The works published in the journal are printed in Polish and English. Terms and Conditions for publishing manuscripts in the quarterly are available on the website www.cppsych.umlub.pl in the tab "Requirements".