Intima-media thickness of the carotid artery in OSAS patients

Perspectives in Medicine Pub Date : 2012-09-01 DOI:10.1016/j.permed.2012.04.010

Silvia Andonova , Diana Petkova , Yana Bocheva

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引用次数: 3

Abstract

Aim

Evaluate the change of intima-media thickness of the carotid artery in patients suffering from obstructive sleep apnea (OSAS).

Materials and methods

The participants of the study were divided into 2 groups: 27 patients suffering from OSAS and a control group of 27 participants (mean age 56.1 ± 1.4 years), having risk factors (RF) for cerebrovascular diseases (CVD) but not OSAS. The morphology of the artery wall – the thickness of the intima media complex (IMT) of the common carotid arteries (CCA), the presence of atherosclerotic plaques, their magnitude, echogenicity and stability were determined with color-coded duplex sonography of the main arteries of the head.

Results

In the OSAS group, CCA-IMT was significantly increased when compared with the non-OSAS patients with RF for CVD, which correlated with the night hypoxemia level. Additionally, the formation of plaques was more pronounced and carotid stenoses were more common in the OSAS patients.

Discussion

These findings are in favor of an independent influence of obstructive sleep apnea on carotid artery atherosclerosis.

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OSAS患者颈动脉内膜-中膜厚度

目的观察阻塞性睡眠呼吸暂停(OSAS)患者颈动脉内膜-中膜厚度的变化。材料与方法将研究对象分为2组:27例OSAS患者和对照组27例(平均年龄56.1±1.4岁)，均有脑血管疾病(CVD)危险因素(RF)，但无OSAS。动脉壁的形态-颈总动脉(CCA)的内膜中膜复合体(IMT)的厚度，动脉粥样硬化斑块的存在，它们的大小，回声强度和稳定性用头部主要动脉的彩色编码双工超声来确定。结果OSAS组CCA-IMT明显高于非OSAS组RF合并CVD患者，且与夜间低氧血症水平相关。此外，斑块的形成更明显，颈动脉狭窄在OSAS患者中更常见。这些发现支持阻塞性睡眠呼吸暂停对颈动脉粥样硬化的独立影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Perspectives in Medicine

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