Carbamazepine-Induced Nonepileptic Myoclonus in a Child with Autism and Epilepsy

IF 0.2 Q4 PEDIATRICS

Journal of Pediatric Epilepsy Pub Date : 2021-01-20 DOI:10.1055/s-0040-1721731

S. Kırık, U. Yiş

引用次数: 2

Abstract

Abstract This study deals with a child with different type of seizures several times in week and unresponsive to antiepileptic drugs. Distinguishing between epileptic seizure and motor tic in a patient diagnosed with epilepsy and autism can be challenging. In this study we presented a male child patient on carbamazepine (CBZ) therapy. In the first days of treatment seizure frequency decreased, but after CBZ treatment dosage reached 15 mg/kg/day (at the 25th day of the treatment), the patient presented to the clinic describing several episodes of myoclonus. There were no changes in electroencephalography during the myoclonus. In follow-up, myoclonus was not described after the cessation of CBZ.

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卡马西平诱导的非癫痫性肌阵挛患儿的自闭症和癫痫

摘要本研究涉及一名儿童，不同类型的癫痫发作在一周内多次，抗癫痫药物无反应。在被诊断为癫痫和自闭症的患者中，区分癫痫发作和运动性抽搐是具有挑战性的。在这项研究中，我们提出了一名男性儿童患者卡马西平(CBZ)治疗。在治疗的头几天癫痫发作频率下降，但在CBZ治疗剂量达到15mg /kg/天后(治疗的第25天)，患者向诊所描述了几次肌阵挛发作。肌阵挛发作时脑电图无变化。在随访中，停止CBZ后未出现肌阵挛。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Pediatric Epilepsy PEDIATRICS-

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期刊介绍： The Journal of Pediatric Epilepsy is an English multidisciplinary peer-reviewed international journal publishing articles on all topics related to epilepsy and seizure disorders, epilepsy surgery, neurology, neurosurgery, and neuropsychology in childhood. These topics include the basic sciences related to the condition itself, the differential diagnosis, natural history, and epidemiology of seizures, and the investigation and practical management of epilepsy (including drug treatment, neurosurgery and non-medical and behavioral treatments). Use of model organisms and in vitro techniques relevant to epilepsy are also acceptable. Journal of Pediatric Epilepsy provides an in-depth update on new subjects and current comprehensive coverage of the latest techniques used in the diagnosis and treatment of childhood epilepsy.

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