Use of Programmed Multilevel Ventilation as a Superior Method for Lung Recruitment in Heart Surgery

C. Peter, Kolesar Adrian, N. Martin, P. Matus, Sabol Frantisek, D. Viera, Donic Viliam, Torok Pavol
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引用次数: 6

Abstract

Objectives: During cardiac surgery, extracorporeal circulation (ECC) causes lung injury. In these inhomogenously affected lungs, the pressure control ventilation (PCV) cannot adequately ventilate differently damaged lung compartments. We invented and used original multilevel lung ventilation method named 3-LV based on alternating 3 or more pressure levels, ventilation frequencies and delivered tidal volumes. The goal of this article is to compare lung mechanics in cardiac surgery patient after ECC using standard PCV when compared to 3LV ventilation. Methods: This study was performed on 88 cardiac surgery patients after disconnection from ECC; the patients were randomly (allocation by weekdays) divided into two groups and ventilated by PCV and 3LV. Group 1 (n = 44) started with 1 hour PCV followed by a second hour with the 3-LV mode. Group 2 (n = 44) was ventilated in the reverse order. Measured parameters were statistically evaluated by the Student’s paired t-test. Results: The static compliance (Cst) and PaO2/FiO2 ratio in 3-LV ventilation mode improved by 25-32% (p < 0.01) and 31% (p < 0.01), in group actually ventilated by 3LV ventilation. The respiratory rate after weaning in Group 1 significantly decreased compared with that in Group 2 (p < 0.05). An improved CO2 washout was observed in each group after switching to 3LV. Conclusions: 3-LV showed a better lung recruitment ability compared with PCV in patients after cardiac surgery, without using high PEEP level.
程序多级通气作为心脏外科肺补充的优越方法
目的:在心脏手术中,体外循环(ECC)引起肺损伤。在这些不均匀的肺中,压力控制通气(PCV)不能充分通气不同损伤的肺室。我们发明并使用了独创的基于3个或3个以上压力水平、通气频率和输送潮气量交替进行的多级肺通气方法3- lv。本文的目的是比较采用标准PCV和3LV通气的心脏手术患者ECC后的肺力学。方法:本研究对88例心脏手术患者进行研究;随机(按工作日分配)分为两组,分别采用PCV和3LV通气。第1组(n = 44)以1小时PCV开始,然后以3-LV模式进行第二小时。第2组(n = 44)逆序通气。测量参数采用学生配对t检验进行统计评估。结果:3LV通气组静态顺应性(Cst)和PaO2/FiO2比实际通气组分别提高25 ~ 32% (p < 0.01)和31% (p < 0.01)。1组断奶后呼吸频率显著低于2组(p < 0.05)。切换到3LV后,每组的CO2洗涤都有所改善。结论:心脏手术后3-LV较PCV表现出更好的肺补充能力,且无高PEEP。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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