Vitamina D en enfermedades respiratorias: desde la influenza hasta el COVID-19

Alonso Cortina-Gutiérrez, Víctor Leal-Martínez, Emilio Abuabara-Franco, Nehomar Pájaro-Galvis, Maria Raad-Sarabia, Jorge-Eduardo Rico-Fontalvo, Rodrigo Daza-Arnedo, Iván de Jesús-Baños
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Abstract

Active vitamin D (1,25-dihydroxycholecalciferol) is a steroid hormone that has multiple functions, including: calcium-phospho-rus metabolism and bone mineralization; but, it also has a fundamental role in the functioning of the immune system, being an essential tool in the response against bacterial infections (including mycobacteria), fungi and viruses. A strong association between hypovitaminosis D and the development of respiratory tract infections such as pneumonia, tuberculosis, influenza virus infection, up to the current pandemic COVID-19 has been demonstrated. Hence the importance of identifying patients with vitamin D deficiency early, in order to correct their levels and prevent infectious processes that increase morbidity and mortality.
呼吸系统疾病中的维生素D:从流感到COVID-19
活性维生素D(1,25-二羟基胆钙化醇)是一种具有多种功能的类固醇激素,包括:钙磷代谢和骨矿化;但是,它在免疫系统的功能中也起着重要作用,是对抗细菌感染(包括分枝杆菌)、真菌和病毒的重要工具。已证实维生素D缺乏症与肺炎、结核病、流感病毒感染等呼吸道感染的发展之间存在密切关联,直至目前的COVID-19大流行。因此,及早发现维生素D缺乏症患者非常重要,以便纠正其水平并预防增加发病率和死亡率的感染过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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