The activator time. A method for control of activator activity during thrombolytic therapy.

Abstract

A simple and rapid method for evaluation of activator activity in patients during thrombolytic therapy-the activator time-is presented. It is based upon a clot lysis system with an euglobulin solution from normal plasma as substrate, but fibrinogen could also be used. The method may tell whether the patient is sufficiently treated or not, and the possibility of establishing a therapeutical range is suggested.