Treatment of ocular surface squamous neoplasia with topical 1% 5-fluorouracil

Abstract

Ocular surface squamous neoplasia (OSSN) is the most common type of ocular tumour. An eighty-year-old man with an elevated lesion in the right eye was diagnosed to have OSSN. 1% topical 5-FU was started as an intermittent treatment. Examination during each visit showed consistent reduction in size of lesion. The patient showed complete regression with no recurrence following treatment with 1% 5-FU at 3 months from presentation. Tropical treatment with 1% 5-FU provides excellent prognosis in cases of OSSN.