Clinical Studies on the Termination of Pregnancy by the Vaginal Administration of 16, 16‐Dimethyl—Trans—Δ2‐PGE1 methyl Ester (ONO 802)

Abstract

A prostagladin analogue, 16-16-Dimethyl-trans-Δ2-PGE1 methyl ester from ONO Pharmaceutical Co., Ltd. was studied by the vaginal administration of suppositories for termination of early and 2nd trimesters of pregnancy. Clinical efficacy and side effects were observed and evaluated.