Factors related to non-adherence to antiretroviral treatment in children under 13 years of age

IF 2.4 Q3 PHARMACOLOGY & PHARMACY
Eva María López -De La Espriella, Hiltony Stanley Villa-Dangond, Camilo Guzmán
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引用次数: 0

Abstract

Background: The Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome (HIV/AIDS) constitute one of the main public health problems worldwide. With the appearance of antiretroviral treatments (ART), the history of the disease has changed, going from being highly fatal to being considered a chronic disease, since these drugs contribute to improving the quality of life of these patients by preventing replication viral. Objective: To identify adherence to antiretroviral treatment in children under 13 years of age living with HIV/AIDS. Methods: Descriptive, retrospective study with a quantitative approach. The population was made up of 21 children under 13 years of age living with HIV/AIDS and their family caregivers. The “Morisky Medication Adherence Scale-8 items (MMAS-8)” was used, and the SPSS statistical program was used for data processing. Version 21. Results: The majority of minors are unaware of the diagnosis (86%), are female (57.1%), live with their biological parents (81%), whose parents or caregivers earn less than the current minimum monthly wage (90.5 %), level of education of the primary caregiver complete (61.9%), non-adherent to antiretroviral treatment (71.4%) the factors associated with non-adherence identified are socioeconomic (Significance 0.004), and those associated with side effects of medications, which were estimated using the Chi square test for categorical variables and the T Student test for quantitative variables, selecting an α=0.05 and a confidence level of 95%. Conclusions: Poverty is a conditioning factor for practices that lead to non-adherence to antiretroviral treatment
13岁以下儿童不坚持抗逆转录病毒治疗的相关因素
背景:人类免疫缺陷病毒和获得性免疫缺陷综合症(HIV/AIDS)是世界范围内主要的公共卫生问题之一。随着抗逆转录病毒治疗(ART)的出现,该疾病的历史发生了变化,从高度致命的疾病转变为被认为是一种慢性疾病,因为这些药物通过防止病毒复制有助于改善这些患者的生活质量。目的:确定13岁以下艾滋病毒/艾滋病儿童抗逆转录病毒治疗的依从性。方法:采用描述性、回顾性定量研究方法。人口由21名13岁以下感染艾滋病毒/艾滋病的儿童及其家庭照顾者组成。采用《Morisky药物依从性量表-8 (MMAS-8)》,采用SPSS统计程序进行数据处理。版本21。结果:大多数未成年人不知道诊断(86%),是女性(57.1%),与亲生父母住在一起(81%),其父母或照顾者的收入低于目前的最低月工资(90.5%),主要照顾者的教育水平完整(61.9%),抗逆转录病毒治疗不坚持(71.4%)。确定的不坚持治疗的相关因素是社会经济(显著性0.004),以及与药物副作用相关的因素。对分类变量采用卡方检验,对定量变量采用T - Student检验,选择α=0.05,置信水平为95%。结论:贫困是导致不坚持抗逆转录病毒治疗的一个条件因素
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来源期刊
Pharmacy Practice-Granada
Pharmacy Practice-Granada PHARMACOLOGY & PHARMACY-
CiteScore
3.90
自引率
4.00%
发文量
113
审稿时长
20 weeks
期刊介绍: Pharmacy Practice is a free full-text peer-reviewed journal with a scope on pharmacy practice. Pharmacy Practice is published quarterly. Pharmacy Practice does not charge and will never charge any publication fee or article processing charge (APC) to the authors. The current and future absence of any article processing charges (APCs) is signed in the MoU with the Center for Pharmacy Practice Innovation (CPPI) at Virginia Commonwealth University (VCU) School of Pharmacy. Pharmacy Practice is the consequence of the efforts of a number of colleagues from different Universities who belief in collaborative publishing: no one pays, no one receives. Although focusing on the practice of pharmacy, Pharmacy Practice covers a wide range of pharmacy activities, among them and not being comprehensive, clinical pharmacy, pharmaceutical care, social pharmacy, pharmacy education, process and outcome research, health promotion and education, health informatics, pharmacoepidemiology, etc.
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