Clinico Pathological Analysis of Nodular Goiter: A Retrospective Study

Abstract

This retrospective study was conducted to evaluate the clinico-pathological pattern of nodular goiter among patients who underwent thyroidectomy. This study included 50 patients following selection criteria. All patients were properly evaluated by history, clinical examination along with blood chemistry, ultrasonography, nuclear scanning and histopathology [fine needle aspiration cytology (FNAC)]. Out of 50 patients 38 were females and 12 were males, the male to female ratio was 1:3.12. Majority of the patients nodule and rest 3 cases were carcinoma. Among total study patients 46 were cold nodules and 4 were warm nodules. Histopathological reports of excised tissues revealed that 45 cases were papillary adenoma, 3 cases were papillary carcinoma and 2 cases were follicular carcinoma. The study concluded that solitary thyroid nodules are frequent at the middle age and predominant among females. Most of the patients of thyroid goiter are in euthyroid state and majority of nodules are benign lesions. Papillary adenoma is the most frequent benign nodular tumor followed by papillary carcinoma and then follicular carcinoma.