Investigation the impact of maximum control point on dose calculation in Eclipse treatment planning system for lung SBRT

Sakda Kingkaew, S. Asavaphatiboon, Lukkana Apipunyasopon
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Abstract

Purpose: Choosing an appropriate parameter on the computerized treatment planning systems (TPSs) influences on the accuracy of dose calculation. Several dosimetric parameters have been studied to achieve a more accurate dose and qualitative plan. The purpose of this study was to determine the impact of maximum control point on the dose calculation on Eclipse TPSs for lung Stereotactic Body Radiation Therapy (SBRT) considering the plan quality, the computation time and the treatment file size. Methods: Dose distributions for the 8 lung SBRT plans with varying maximum control point of 64, 166, and 320 were calculated by Eclipse TPSs with flattening filter free (FFF) beam. The treatment dose was prescribed at 85% isodose level of 54 Gy to the planning target volume (PTV). The dosimetric impact can be evaluated from target coverage, conformity index (CI), homogeneity index (HI), and organ at risk (OAR) doses, while the computation time and the file storage space were compared with the recommended number of control point. Results: The use of 64 control points per subfields tended to increase the dose at PTV and OARs comparing with the 166 and 320 control point plans, while the HI and CI values were similar. The average increases of OARs doses including the spinal cord, heart, esophagus and total lung depended on the photon beam energy. The higher average control point (AVG) number leaded to increase the computation time and the file size for both 6X-FFF and 10X-FFF photon beams. The correlations between AVG and plan storaage space were observed in the same ratio as the computation time. Conclusion: Using the minimal number of control point, the quantitative analysis in the PTV and OARs showed no clinically significant variation in dose, therefore choosing an optimal number of fixed control points leaded to balance the plan quality, the computation time and the file size.
探讨Eclipse肺SBRT治疗计划系统中最大控制点对剂量计算的影响
目的:计算机化治疗计划系统(tps)参数的选择对剂量计算精度的影响。研究了几个剂量学参数,以获得更准确的剂量和定性计划。本研究的目的是在考虑计划质量、计算时间和治疗文件大小的情况下,确定最大控制点对Eclipse tps用于肺立体定向放射治疗(SBRT)剂量计算的影响。方法:采用带FFF光束的Eclipse tps计算最大控制点为64,166和320的8种肺SBRT方案的剂量分布。治疗剂量为计划靶体积(PTV)的85%等剂量54 Gy。剂量学影响可从靶覆盖率、符合性指数(CI)、均匀性指数(HI)和器官危险剂量(OAR)进行评价,并将计算时间和文件存储空间与推荐控制点数进行比较。结果:每子野64个控制点与166个和320个控制点相比,有增加PTV和OARs剂量的趋势,而HI和CI值相近。包括脊髓、心脏、食道和全肺在内的OARs剂量的平均增加取决于光子束能量。较高的平均控制点(AVG)数导致6X-FFF和10X-FFF光子光束的计算时间和文件大小增加。AVG与计划存储空间的相关比例与计算时间的相关比例相同。结论:采用最小数量的控制点,PTV和OARs的定量分析显示剂量没有临床意义上的变化,因此选择最佳数量的固定控制点可以平衡计划质量、计算时间和文件大小。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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