Association Between Epicardial Adipose Tissue and Atrial Fibrillation

Abstract

Several lines of evidence have shown that epicardial adipose tissue（EAT）is related to the presence, severity, and outcome of atrial fibrillation（AF）. Mechanistically, studies have suggested that the effects of EAT may be mediated by local cytokines/chemokines, inflammation, and fatty infiltration. Here, we discuss the role of EAT, especially in its effect on atrial myocardial fibrosis. Prevention of qualitative alteration of EAT may be a novel therapeutic target for AF.