Weight Management: Inflammation

Abstract

Nowadays, obesity is considered as one of the fastest escalating nutritional disorders that reached pandemic throughout the world. Obesity is a condition in which overaccumulation of energy in the form of fat happens in an individual’s subcutaneous and/or abdominal visceral tissue. It is described as an abnormal growth of adipose tissue due to the enlargement of fat cell size (hypertrophic obesity) or fat cell number (hyperplastic obesity) or a condition of both. Earlier, it was reported that the most common type of obesity that affects the general popula-tion is the polygenic form that results from a result of a positive energy balance between energy consumption and its expenditure – or a combination of both. The pandemic of obesity has enforced to analyze the link between the role of inflammation and complications of overweight and obesity. This led to crossroads of the field of nutrition, diet therapy, physiology, immunology, and epidemiology and makes the understanding that they are linked inexplicably. The remodeling of obesity as an inflammatory state has led a wide impression in our conceptualization of obesity-related diseases. In this chapter, we highlight the endocrine aspect of adipose tissue, the effect of dysregulated secretion of adipokines due to inflammation and dietary components that affect obesity related to inflammation.