Anti-Inflammatory and Antimicrobial Activities of Powered and Ethanaol Extracts of Scent Leaf (Ocimum gratissimum) and Curry Leaf (Murraya koenigii)

International Letters of Chemistry, Physics and Astronomy Pub Date : 2020-12-01 DOI:10.18052/www.scipress.com/ilcpa.85.15

E. L. Onyeyilim, M. A. Ezeokonkwo, C. Uzoewulu, F. U. Eze, Festus Chinonso Urama, C. C. Eze, V. O. Okonkwo, I. Otunomo

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Abstract

In this manuscript, the authors explore the antimicrobial and anti-inflammatory properties of extracts from two commonly found and used leaves from species Murraya koenigii and Ocimum gratissimum L., Ethanolic extracts were obtained by maceration and were then concentrated. Serial dilutions of the extracts were done for testing. The extracts were tested for growth inhibition of four bacterial and two fungal strains. Visual examination of growth inhibition, compared to standard antibiotic controls, provided minimum inhibitory concentrations for the two extracts against the six microbial strains. In another experiment, the authors test the anti-inflammatory properties of the two leaf extracts in the standard rat-paw model of inflammation. Results from growth inhibition studies suggest that the two leaf extracts inhibit the growth of all six microbes, with varying levels of sensitivity. Results from anti-inflammatory studies are more impressive, with leaf extracts inhibiting inflammation at levels competitive with the standard drug, indomethacin.

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香叶和咖喱叶动力提取物和乙醇提取物的抗炎和抗菌活性

在这篇文章中，作者探索了两种常见和使用的植物Murraya koenigii和Ocimum gratissimum L.的叶子提取物的抗菌和抗炎特性，乙醇提取物通过浸渍得到，然后浓缩。连续稀释提取物进行测试。对四种细菌和两种真菌进行了抑菌试验。与标准抗生素对照相比，生长抑制目视检查提供了两种提取物对六种微生物菌株的最低抑制浓度。在另一项实验中，作者在标准的大鼠爪子炎症模型中测试了两种叶子提取物的抗炎特性。生长抑制研究的结果表明，两种叶子提取物抑制所有六种微生物的生长，具有不同程度的敏感性。抗炎研究的结果更令人印象深刻，叶子提取物抑制炎症的水平与标准药物吲哚美辛相当。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International Letters of Chemistry, Physics and Astronomy

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