Facile Access to Aldol Products from Aromatic and Heteroaromatic Aldehydes Using Ruthenium Catalyst

Abstract

A new method for the synthesis of aldol products is described. The reaction of aromatic and heteroaromatic aldehydes with 1-(thiophen-2-yl)ethanone in the presence of ruthenium chloride hydrate combined with ligand provided the related aldol adducts, in a short time at room temperature in good yields (77–84%).