Anti-Psychotic Medication and the Pattern of Cardiovascular Risk Factors: A Population Based Study (The Ayrshire Diabetes Follow-Up Cohort (ADOC) Study)

A. Collier, Karthigayan Kessavalou, L. Sit, M. Hair, Lyall Cameron, A. Abdeen
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Abstract

Background: Life expectancy in people with severe mental illness is significantly reduced: in part due to increased cardiac risk. Aim: The aims of this study were to investigate the prevalence of cardiovascular risk factors and to determine the prevalence of regular screening in these patients. Method: Data was extracted from 48 General Practices in NHS Ayrshire and Arran (n=320,613) in April 2015. Results: There were 3857 patients on anti-psychotic medication (prevalence 1.2%). Female patients and those on first generation medication were older (p<0.001). Monitoring rates ranged from 75% for BP and smoking down to under 50% for lipids. Only 10% of patients monitored were free of a cardiovascular risk factor. Conclusion: Treatment with anti-psychotic medication was associated with clustering of cardiovascular risk factors. Screening varied in relation to age and sex of the patient, the anti-psychotic agent prescribed and cardiovascular risk factor.
抗精神病药物与心血管危险因素模式:一项基于人群的研究(Ayrshire糖尿病随访队列(ADOC)研究)
背景:严重精神疾病患者的预期寿命显著降低:部分原因是心脏风险增加。目的:本研究的目的是调查心血管危险因素的患病率,并确定这些患者定期筛查的患病率。方法:数据提取自2015年4月艾尔郡和阿伦郡NHS的48个全科医生(n=320,613)。结果:共3857例患者接受抗精神病药物治疗,患病率1.2%。女性患者和第一代用药患者年龄较大(p<0.001)。监测率从血压和吸烟的75%到血脂的50%以下不等。只有10%的监测患者没有心血管危险因素。结论:抗精神病药物治疗与心血管危险因素聚类相关。筛查与患者的年龄和性别、抗精神病药物处方和心血管危险因素有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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