Coronary artery bypass grafting with the internal thoracic artery in patients over age 70

Kanji Kawachi MD, Soichiro Kitamura MD, Ryuichi Morita MD, Shigeki Taniguchi MD, Masaaki Fukutomi MD, Tetsuji Kawata MD, Junichi Hasegawa MD, Yoshiaki Kondo MD
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引用次数: 1

Abstract

The objective of this study was to determine whether there was higher mortality and morbidity in patients older than 70 years of age compared to those younger than 70 years who had coronary artery bypass grafting (CABG). The second objective was to determine whether the internal thoracic artery (ITA) grafts in patients aged more than 70 years were safe and beneficial. Patients were divided into 2 groups: “elderly” (125 patients aged 70 years or more) or “younger” (765 patients younger than 70 years). Early and long-term results and the incidence of postoperative complications were compared. The elderly group was subdivided into 96 patients in whom ITA grafts were used for CABG (elderly ITA) and 29 patients in whom only saphenous vein grafts (SVG) were used (elderly SVG). Hospital mortality was higher in elderly patients than in younger patients. There was no significant difference in hospital mortality between elderly ITA and elderly SVG patients. The incidence of postoperative complications was higher in elderly patients than younger patients. When comparing postoperative surgical complications between elderly ITA and elderly SVG patients, no significant differences were noted. Although the mortality after CABG was slightly higher in elderly patients than in younger patients, most of the elderly long-term survivors were able to lead ordinary lives. These results suggest that the use of the ITA in elderly patients did not increase the operative risk and postoperative surgical complications, and may have reduced the incidence of late cardiac events.

70岁以上患者的胸内动脉冠状动脉旁路移植术
本研究的目的是确定70岁以上患者的死亡率和发病率是否高于70岁以下患者的冠状动脉旁路移植术(CABG)。第二个目的是确定70岁以上患者的胸内动脉(ITA)移植是否安全有益。患者分为两组:“老年”组(125例70岁及以上)和“年轻”组(765例70岁以下)。比较两组的早期、远期疗效及术后并发症的发生率。老年组再细分为96例使用ITA进行CABG(老年ITA)和29例仅使用隐静脉(SVG)进行CABG(老年SVG)。老年患者的住院死亡率高于年轻患者。老年ITA与老年SVG患者住院死亡率无显著差异。老年患者术后并发症发生率高于年轻患者。老年ITA患者与老年SVG患者术后手术并发症比较,无明显差异。尽管老年患者CABG后的死亡率略高于年轻患者,但大多数老年长期幸存者能够过正常的生活。这些结果提示,在老年患者中使用ITA不会增加手术风险和术后手术并发症,并可能降低了晚期心脏事件的发生率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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