Can definitive chemoradiation offer a cure along with cosmesis in locally advanced IVA carcinoma buccal mucosa? a case report

International Journal of Clinical Trials Pub Date : 2023-07-26 DOI:10.18203/2349-3259.ijct20232201

J. Sharma, M. Gupta, Siddharth Vats, Naina Negi

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Abstract

Surgery is the mainstay of the treatment in ca buccal mucosa. It is extensive in nature and may require efficient reconstruction for good cosmetic outcome. Adjuvant radiation or chemo-radiation may be needed in advanced cancers. Definitive chemoradiation or palliative radiation are reserved for inoperable patients. We present a case report of advanced carcinoma of oral cavity in the left buccal mucosa along with involvement of retromolar trigone along with bone involvement in left sided mandible who opted out for undergoing definitive surgery. She was treated with definitive chemoradiation with 2.4 Gy per day /0.4 Gy in morning, 2 Gy in evening five days a week along with paclitaxel on Sunday. Patient reported after seven years disease free with excellent cosmetic outcome. Definitive surgery along with adjuvant radiation or chemoradiation is the standard of care in advanced cancers of buccal mucosa. However, in inoperable patients or the patients refusing surgery definitive chemoradiation with altered fractionation schedules may still offer a chance of cure and good cosmesis.

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局部晚期IVA颊粘膜癌，明确的放化疗和美容能治愈吗?病例报告

手术是治疗颊部粘膜病变的主要方法。它本质上是广泛的，可能需要有效的重建以获得良好的美容效果。晚期癌症可能需要辅助放疗或化学放疗。最终的放化疗或姑息性放化疗是为不能手术的患者保留的。我们报告了一例晚期口腔癌左颊粘膜伴磨牙后三角区累及左侧下颌骨骨累及的病例，并选择接受最终手术。患者接受确定性放化疗，每天2.4 Gy /早0.4 Gy，晚2gy，每周5天，周日紫杉醇治疗。患者报告七年后无疾病，良好的美容效果。晚期口腔黏膜癌的标准治疗方法是手术配合辅助放疗或放化疗。然而，对于不能手术的患者或拒绝手术的患者，改变分割时间表的明确放化疗仍可能提供治愈和良好美容的机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International Journal of Clinical Trials

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