Prognosis of diabetic coronary artery bypass graft surgery patients

I. Moursi, K. Al Fakharany
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引用次数: 4

Abstract

Background

Diabetes mellitus (DM) is considered as mortality and morbidity risk factor for coronary artery bypass graft surgery (CABG). Studies revealed that there are controversies concerning the results of a post coronary surgery diabetic patients. The aim of our study was the evaluation of the short-term outcomes in this group of patients.

Methods

This was a single-center retrospective study of 180 patients that were subjected to CABG between January 2014 and January 2016 in Zagazig University Hospital, Zagazig, Egypt. Sixty-one patients (34%) were diabetic (group I) and 119 patients (66%) were non-diabetic (group II). During follow-up period the hospital mortality, complications and major cardiovascular events were analyzed. All patients admitted with a diagnosis of diabetes had an HbA1c ≥ 6.5% or fasting blood glucose (FBG) ≥ 126 mg/dL (7.0 mmol/L).

Results

Operative mortality was 3% (n = 2) in the diabetic group and 1% (n = 1) in non-diabetic patients (p = 0.3). Euro score was predictably higher in diabetic patients (1.2 vs 0.84, p = 0.001). The study of the risk factors associated with hospital complications revealed that the absence of diabetes was a protective factor for hospital complications but statistically insignificant. The rate of major cardiovascular events at 2 years period of follow-up in diabetic and non-diabetic groups was (12/50) 24% and (16/93)17%, respectively (p = 0.43).

Conclusions

The improvement in management of DM patients leads to acceptable operative mortality post-CABG and decrease the incidence of complications and events in the short-term follow-up period.

糖尿病冠状动脉搭桥术患者的预后
背景糖尿病(DM)被认为是冠状动脉搭桥手术(CABG)的死亡率和发病率的危险因素。研究表明,对冠状动脉手术后的糖尿病患者的结果存在争议。我们研究的目的是评估这组患者的短期预后。方法对2014年1月至2016年1月在埃及Zagazig大学医院行CABG的180例患者进行单中心回顾性研究。1组为糖尿病患者61例(34%),2组为非糖尿病患者119例(66%)。随访期间对住院死亡率、并发症及主要心血管事件进行分析。所有诊断为糖尿病的住院患者HbA1c≥6.5%或空腹血糖(FBG)≥126 mg/dL (7.0 mmol/L)。结果糖尿病组手术死亡率为3% (n = 2),非糖尿病组手术死亡率为1% (n = 1) (p = 0.3)。糖尿病患者的Euro评分可预测较高(1.2 vs 0.84, p = 0.001)。对医院并发症相关危险因素的研究显示,无糖尿病是医院并发症的保护因素,但统计上不显著。2年随访期间,糖尿病组和非糖尿病组的主要心血管事件发生率分别为(12/50)24%和(16/93)17% (p = 0.43)。结论改善对糖尿病患者的管理,可使冠脉搭桥术后的手术死亡率达到可接受的水平,短期随访期间并发症和事件的发生率降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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