Y. Ogawa, S. Yoshihara, Toshihiko Nagata, Taisuke Akiyama, J. Kumasawa, M. Kono, H. Kohata, K. Nishida, I. Gohma
{"title":"A Case of COVID-19 Pneumonia in an 83-year-old Woman Living with a Suspected SARS-CoV-2 Carrier, Who Repeatedly Tested Negative by the PCR Test","authors":"Y. Ogawa, S. Yoshihara, Toshihiko Nagata, Taisuke Akiyama, J. Kumasawa, M. Kono, H. Kohata, K. Nishida, I. Gohma","doi":"10.11150/KANSENSHOGAKUZASSHI.94.542","DOIUrl":null,"url":null,"abstract":"The patient, an 83-year-old woman, lived with her daughter, at whose workplace, a person had been diagnosed as having COVID-19 The daughter was admitted to the hospital for pneumonia, however, the results of the PCR test for SARS-CoV-2 performed twice were negative The patient developed fever a few days later, and visited an outpatient clinic for patients with fever and a history of travel abroad The result of a nasal swab PCR test was negative, and antibiotics were prescribed While the fever gradually subsided, the patient began to experience dyspnea Therefore, she visited the outpatient clinic again for a repeat nasal swab test Meanwhile, the dyspnea became severe and she was transported to our hospital Immediately after admission, she was intubated and initiated on mechanical ventilation A nasal swab and a specimen of lower respiratory tract secretions were submitted for COVID-19 testing by PCR, and while the nasal swab test result was negative again, the lower respiratory tract specimen yielded a positive result�E�EThe possibility of false-negative results of PCR testing for SARS-CoV-2 should be borne in mind in close contacts or strongly suspected cases of COVID-19 PCR testing of specimens of lower respiratory tract secretions might be necessary for suspected cases of COVID-19 pneumonia","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.542","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The patient, an 83-year-old woman, lived with her daughter, at whose workplace, a person had been diagnosed as having COVID-19 The daughter was admitted to the hospital for pneumonia, however, the results of the PCR test for SARS-CoV-2 performed twice were negative The patient developed fever a few days later, and visited an outpatient clinic for patients with fever and a history of travel abroad The result of a nasal swab PCR test was negative, and antibiotics were prescribed While the fever gradually subsided, the patient began to experience dyspnea Therefore, she visited the outpatient clinic again for a repeat nasal swab test Meanwhile, the dyspnea became severe and she was transported to our hospital Immediately after admission, she was intubated and initiated on mechanical ventilation A nasal swab and a specimen of lower respiratory tract secretions were submitted for COVID-19 testing by PCR, and while the nasal swab test result was negative again, the lower respiratory tract specimen yielded a positive result�E�EThe possibility of false-negative results of PCR testing for SARS-CoV-2 should be borne in mind in close contacts or strongly suspected cases of COVID-19 PCR testing of specimens of lower respiratory tract secretions might be necessary for suspected cases of COVID-19 pneumonia