Relationship Between Geometry and Ventricular Filling Pressures in Non-Diabetic Hypertensive Patients

Abstract

Hypertension and obesity make changes in the heart that are known as remodeling and diastolic dysfunction. These changes are the beginning of a later sistolic heart failure. Objectives Searching for the relation between geometry and ventricular function in hypertensive non diabetic and obese patients. 68 women and 20 men were evaluated by doppler- echocardiography. All patients had a normal ejection fraction. Results Ventricular geometry was altered in 53.4% of the subjects and diastolic function in 73.8% respectively. As body weight increased the ventricular mass, relative wall thickness, left atrial dimension and end diastolic volumes increased too. Overweight and obesity were found in 62.5% of the sample. A concentric left ventricular hypertrophy was present in 27.2% of the patients. An excentric left ventricular hypertrophy was found in 14.7% of them and 46.6% had a normal geometry. Eyection fraction values were lesser in the group with bigger ventricular mass and altered filling patterns. P=0.05, 0.1. Conclusion Arterial hypertension and obesity are risk factors for the development of cardiac abnormalities that lower systolic cardiac function in case of hypertrophy and dilatation are not resolved.