A Model-based Method for Measuring Autonomic Nerve Activity and Sensitivity

Abstract

The measurement of autonomic nerve activity plays an important role in the diagnosis and treatment of various cardiovascular diseases. This paper presents a model-based method for measuring autonomic nerve activity and sensitivity. By non-invasively recording heart rate and blood pressure data of the subjects during the sit-to-stand experiment, we modeled the blood pressure-heart rate regulation system and solved personalized parameters. These personalized parameters were used to obtain the autonomic nerve activity and sensitivity of the subjects. We conducted experiments on 9 patients with refractory hypertension and 20 healthy people, and the results showed that there were significant differences in the sensitivity and activity of autonomic nerves.