Stimulation of thyroid cell growth by thyrotropin and epidermal growth factor in isolated porcine thyroid follicles.

Abstract

[3H]thymidine incorporation during culture of thyroid follicles isolated from porcine glands (Schatz et al. 1983, 1986) can be taken for estimating thyroid growth stimulating immunoglobulins (TGI) (Drexhage et al. 1980; Chiovato et al. 1983; Valente et al. 1983). In this study we wanted to characterize our assay system in order to answer the question whether TSH itself was responsible for stimulation of [3H]thymidine incorporation observed when using TSH as standard in