SCORING SCALE FOR ASSESSING THE RISK OF DETECTING RIGHT VENTRICLE DIASTOLIC DYSFUNCTION OF TYPE II IN CHRONIC HEART FAILURE

O. M. Zherko, E. I. Shkrebneva, P. Novikov, A. Babenka, V. Gorbachev, M. Kosova, A. Kabanava, N. A. Averchankava
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Abstract

Odjectives. To develop a scoring scale for assessing the risk of detecting right ventricle (RV) diastolic dysfunction (DD) of type II in chronic heart failure (CHF). Material and methods. In 2017-2018, a clinical and instrumental examination of 247 patients aged 40-86 years was performed on the basis of Health Care Institution «The 1st City Clinical Hospital» in Minsk, in 2019-2020, 129 patients at the age of 39-84 years were examined in the State Institution «Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology». Study inclusion criteria: sinus rhythm, essential arterial hypertension (AH), chronic ischemic heart disease (IHD), CHF, informed voluntary consent of the patient to participate in the study. Exclusion criteria: primary mitral regurgitation, mitral stenosis, mitral valve repair or replacement, congenital heart defects, acute and chronic diseases of the lungs and kidneys. Results. The sum of points>52 obtained using a scoring scale that includes scientifically based ultrasound criteria for global cardiac remodelling: RV early diastolic filling index E/eʹ >4.08 (sensitivity (S) 81.1%, specificity (Sp) 56.9%) - 15 points, the amplitude of the systolic displacement of the lateral part of the tricuspid annulus in systole to the apex (TAPSE) ≤20 mm (S 74.1%, Sp 83.3%) - 49 points, pulmonary artery systolic pressure ˃32.6 mm Hg (S 85.2%, Sp 79.5%) - 31 points, indicates a high risk of detecting RV DD of type II in CHF (AUC 0.99, S 93.9%, Sp 100.0%). The reproducibility of the results is shown in an independent examination sample of patients with CHF with preserved left ventricular ejection fraction. (AUC 0.99, S 90.0%, Sp 100%, +PV 100.0%, - PV 34.5% with a cut-off threshold >52). Conclusions.When using the scale, the score is > 52, it is recommended to perform a comprehensive targeted assessment of global cardiac remodelling to determine RV DD of type II in a patient with CHF, complicating essential AH, chronic IHD.
慢性心力衰竭患者ii型右心室舒张功能不全风险评估评分量表
Odjectives。建立慢性心力衰竭(CHF)患者ⅱ型右心室(RV)舒张功能障碍(DD)检测风险的评分量表。材料和方法。2017-2018年,在明斯克“第一城市临床医院”医疗机构对247名40-86岁的患者进行了临床和仪器检查,2019-2020年,129名39-84岁的患者在国立机构“明斯克外科、移植和血液学科学和实践中心”进行了检查。研究纳入标准:窦性心律、原发性动脉高血压(AH)、慢性缺血性心脏病(IHD)、CHF,知情自愿同意参加研究的患者。排除标准:原发性二尖瓣返流、二尖瓣狭窄、二尖瓣修复或置换术、先天性心脏缺陷、肺和肾脏急慢性疾病。结果。使用评分量表(包括基于科学的整体心脏重构超声标准)获得的>52分的总和:RV舒张早期充盈指数E/ E′>4.08(敏感性(S) 81.1%,特异性(Sp) 56.9%) 15分,收缩期三尖瓣环外侧收缩位移幅值(TAPSE)≤20 mm (S 74.1%, Sp 83.3%) - 49分,肺动脉收缩压≤32.6 mm Hg (S 85.2%, Sp 79.5%) - 31分,提示诊断CHF型RV DD的风险较高(AUC 0.99, S 93.9%, Sp 100.0%)。在保留左心室射血分数的CHF患者的独立检查样本中显示了结果的重复性。(AUC 0.99, S 90.0%, Sp 100%, +PV 100.0%, - PV 34.5%,临界值>52)。结论。使用该量表时,评分> 52,建议对合并CHF、原发性AH、慢性IHD的患者进行全面有针对性的心脏重构评估,以确定II型RV DD。
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