Tryptophan and kynurenines in neurodegenerative disease

Laura A. Sordillo, P. Sordillo, Lin Zhang, R. Alfano
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Abstract

There is mounting evidence that there exists a connection between abnormal tryptophan metabolism and neurodegenerative diseases. The relationship between tryptophan and kynurenines in 48 age-matched normal and Alzheimer’s disease human brain tissues was investigated using label-free fluorescence spectroscopy.
色氨酸和犬尿氨酸在神经退行性疾病中的作用
越来越多的证据表明,色氨酸代谢异常与神经退行性疾病之间存在联系。用无标记荧光光谱法研究了48例年龄匹配的正常人和阿尔茨海默病患者脑组织中色氨酸和犬尿氨酸的关系。
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