Comparative Study on Antioxidant Activity and Cytotoxicity of Defatted Kernels of Mango (Mangifera indica) and Wild Mango (Irvingia gabonensis and Irvingia wombolu)

Abstract

Defatted kernel powder of mango (Mangifera indica) and wild mango (Irvingia gabonensis and Irvingia wombolu) were analysed for their in-vitro antioxidant activity and cytotoxicity. Dry matter content of the three kernel types were in the range of 93 to 95%. On defatting, the percentage oil yield of the Irvingia varieties were similar and 200% higher than that of Mangifera indica. The antioxidant activity using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) technique showed that the two Irvingia varieties (DIGK and DIWK) had similar IC50 (p>0.05) but significantly higher than that of Mangifera indica kernel (DMIK) (p<0.05). Likewise, results from the Ferric Reducing Antioxidant Power (FRAP) technique and Cytotoxicity assay confirmed the higher potency of DMIK over the Irvingia kernels.