Antioxidant Activity of 96% Ethanol Extract of Pepaya Jepang Leaves (Cnidoscolus aconitifolius (Mill.) I. M. Johnst) Using DPPH Method (1,1-diphenyl-2-picrylhydrazyl)

Borneo Journal of Pharmacy Pub Date : 2022-11-30 DOI:10.33084/bjop.v5i4.3511

Riskianto Riskianto, M. Windi, Karnelasatri Karnelasatri, Maroloan Aruan

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Abstract

Free radicals in the human body can be helped neutralized by natural antioxidants derived from plants. Pepaya Jepang (Cnidoscolus aconitifolius (Mill.) I.M.Johnst) contains antioxidant compounds such as flavonoids and polyphenols. This study examined the antioxidant activity of 96% ethanol extract of C. aconitifolius leaves. Maceration of C. aconitifolius leaves using 96% ethanol solvent, phytochemical screening, and antioxidant activity assay was carried out with 1,1-Diphenyl-2-Picryl Hydrazil (DPPH) on 96% ethanol extract of C. aconitifolius. Extraction obtained a yield of 16.1834%, and phytochemical screening on the 96% ethanol extract of C. aconitifolius contained flavonoids, tannins, saponins, phenols, alkaloids, and steroids. The antioxidant activity assay on 96% ethanol extract of C. aconitifolius had an IC50 value of 145.3855 ppm and an IC50 value of vitamin C of 7.0806 ppm. The Antioxidant Activity Index (AAI) of 96% ethanol extract of C. aconitifolius was 0.4127, and the AAI of vitamin C was 8.4739. Based on the results obtained, although in a weak classification, a 96% ethanol extract of C. aconitifolius leaves has antioxidant activity.

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木参叶96%乙醇提取物的抗氧化活性研究I. M. Johnst) DPPH法(1,1-二苯基-2-吡啶肼基)

从植物中提取的天然抗氧化剂可以帮助中和人体中的自由基。(中国)刺毛线虫含有抗氧化化合物，如类黄酮和多酚。研究了乌头叶96%乙醇提取物的抗氧化活性。采用96%乙醇浸泡乌头叶，用1,1-二苯基-2-苦味子酰肼(DPPH)对96%乙醇提取物进行植物化学筛选和抗氧化活性测定。提取得率为16.1834%，对96%乙醇提取的附子黄酮、单宁、皂苷、酚类、生物碱和甾体进行了植物化学筛选。96%乙醇提取物抗氧化活性的IC50值为145.3855 ppm，维生素C的IC50值为7.0806 ppm。96%乙醇提取物抗氧化活性指数(AAI)为0.4127，维生素C的AAI为8.4739。结果表明，96%乙醇提取物具有较弱的抗氧化活性。

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Borneo Journal of Pharmacy

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