Correlation between Fibroblast Growth Factor 23 and C-reactive Protein in Hemodialysis Patients

Elham Ramezanzade, S. Nikfarjam, Masoomeh Namdar, Fatemeh nejatifar
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Abstract

12.94±8.82. In multiple linear regression analysis, after controlling the effect of confounding variables (individual variables, blood parameters, and underlying diseases), there was a direct and significant relationship between iFGF23 and CRP (P=0.010, 𝜷 =0.129, CI=0.032-0.226). Discussion & Conclusion: The present study showed that increased FGF23 levels are independently associated with increased CRP levels in patients with ESRD. Future studies should evaluate whether inflammation alters the association between elevated FGF23 levels and adverse clinical outcomes in ESRD.
血液透析患者成纤维细胞生长因子23与c反应蛋白的相关性
12.94±8.82。在多元线性回归分析中,在控制混杂变量(个体变量、血液参数、基础疾病)的影响后,iFGF23与CRP存在直接且显著的关系(P=0.010,𝜷=0.129,CI=0.032-0.226)。讨论与结论:本研究表明,FGF23水平升高与ESRD患者CRP水平升高独立相关。未来的研究应该评估炎症是否会改变FGF23水平升高与ESRD不良临床结局之间的关系。
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