SILVER NANO DOTS FUNCTIONALIZED BONE CEMENT FOR ORTHOPAEDIC MEDICAL APPLICATIONS

A.G.J.Patricia, M.Uma Devi mahalingm
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Abstract

The latest development in orthopaedics is the advent of silver nano particles and their applications in nano medicine. Silver nano dots in the size range of ≤ 20 nm can be studied to analyze their usage in the field of orthopaedics. They can be used in bone cement which are used as artificial bpne replacement. Bone cements have been used very successfully to anchor artificial joints like hip joints, knee joints, shoulder and elbow joints in suffering patients in the field of ortho paedic medicine. Polymethyl methacrylate loaded with nanosilver is being considered as bone cement as the nano silver can induce very high antimicrobial activity essential for the killing of infectious microorganisms known for their anti-resistance to currently available antibiotics and antiseptics.The free space between the bone and the prosthesis is filled with bone cement which acts like a elastic buffer zone. This is necessary because the body weight and the bone cement must absorb the forces acting on the body to ensure that the artificial medical implant remains in place over the long term. In this study, we analyze silver nano dots encapsulated bone cement for medical purposes which can prevent surgical infection in replacement surgeries drastically than the methods currently in use. Also in this study it was found due their unique properties they can accelerate the wound healing process at a faster rate than the rest of the conventional methods practiced in the ortho paedics field.
银纳米点功能化骨水泥在骨科医学中的应用
纳米银粒子的出现及其在纳米医学中的应用是骨科领域的最新发展。可以研究尺寸≤20nm的银纳米点,分析其在骨科领域的应用。它们可用于骨水泥,用于人工膝关节置换。骨水泥在矫形儿科医学领域已成功应用于髋关节、膝关节、肩关节、肘关节等人工关节的固定。负载纳米银的聚甲基丙烯酸甲酯被认为是骨水泥,因为纳米银可以诱导非常高的抗菌活性,对于杀死已知对现有抗生素和防腐剂具有抗抗性的感染性微生物至关重要。骨和假体之间的空隙被骨水泥填充,起到弹性缓冲带的作用。这是必要的,因为身体的重量和骨水泥必须吸收作用在身体上的力,以确保人工医疗植入物长期保持在适当的位置。在这项研究中,我们分析了银纳米点封装骨水泥的医疗用途,它可以比目前使用的方法更有效地预防手术感染。此外,在这项研究中发现,由于其独特的性质,它们可以加速伤口愈合过程,其速度比骨科领域其他传统方法更快。
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