Chest wall secondary chondrosarcoma caused by malignant degeneration of an enchondroma: case report and literature review

Q4 Pharmacology, Toxicology and Pharmaceutics

Acta Marisiensis - Seria Medica Pub Date : 2022-03-01 DOI:10.2478/amma-2022-0006

C. Ioniță, I. Cojocaru, A. Gomotirceanu, B. Suciu, D. Milutin, A. A. Molnar, Vlad Neag, I. Halmaciu

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Abstract

Abstract Introduction: Enchondromas are benign tumors originating in the cartilaginous tissue of the hyaline gristle, rarely located in the chest wall. They sometimes undergo a sarcomatous transformation, becoming secondary chondrosarcomas. Case presentation: We present the case of a 53-year-old patient who, following a chest computed tomography scan performed after a thoracic trauma, was diagnosed with an osteolytic tumor at the chondrocostal junction of rib 4. Surgery was performed, with partial straight resection of ribs 3–5. Histopathological examination of the resection piece identified the existence of a chest wall chondrosarcoma on the background of malignant degeneration of an enchondromatosis lesion. The postoperative evolution was favorable, and the patient was discharged on the eighth postoperative day. Conclusion: In patients with even asymptomatic chest wall enchondromas, periodic clinical evaluation of these lesions is required, given their risk of malignant degeneration.

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由内生纤维瘤恶性变性引起的胸壁继发性软骨肉瘤1例报告并文献复习

摘要:内软骨瘤是起源于透明软骨软骨组织的良性肿瘤，很少位于胸壁。它们有时会发生肉瘤转化，成为继发性软骨肉瘤。病例介绍:我们报告一例53岁的患者，在胸部创伤后进行胸部计算机断层扫描，被诊断为肋骨软骨肋交界处的溶骨性肿瘤。手术完成，部分直切除肋骨3-5。组织病理学检查的切除片确定存在胸壁软骨肉瘤的背景下恶性变性的内生纤维瘤病变。术后进展良好，患者于术后第8天出院。结论:即使是无症状的胸壁内生纤维瘤患者，考虑到其恶性变性的风险，也需要对这些病变进行定期临床评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Marisiensis - Seria Medica Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

24 weeks