Fibrous dysplasia of the pediatric anterior maxilla: A case report and review of literature

S. Vasudev, Partha Debnath, S. Deepak, G. R. Maneeshashree
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Abstract

Fibrous dysplasia (FD) is a benign fibro-osseous lesion in which the fibrous connective tissue containing abnormal bone replaces normal bone. FD is linked to GNAS1 guanine nucleotide-binding protein, alpha-stimulating activity peptide 1, and the gene mutation resulting in the abnormal proliferation and differentiation into pre-osteoblast. In this case report, we present a case of 9 years old boy with monostotic FD affecting the left maxilla causing bony expansion and asymmetry of the right side of face.
小儿前上颌骨纤维发育不良:1例报告及文献复习
纤维发育不良(FD)是一种良性纤维骨性病变,其中含有异常骨的纤维结缔组织取代了正常骨。FD与GNAS1鸟嘌呤核苷酸结合蛋白、α -刺激活性肽1以及导致异常增殖分化为成骨前细胞的基因突变有关。在这个病例报告中,我们提出了一个9岁的男孩,单侧FD影响左上颌骨,导致骨扩张和右侧面部不对称。
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