Age and Body Mass Index: the most important factors of urinary and erectile function recovery after robotic assisted radical prostatectomy

L. Favorito
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引用次数: 2

Abstract

The July-August 2019 issue of the International Brazilian Journal of Urology presents original contributions with a lot of interesting papers in different fields: Infertility, Bladder augmentation, Bladder Cancer, PCNL, Prostate Cancer, Renal Cell Carcinoma, Partial nephrectomy, Renal stones, Nocturnal Enuresis, Basic Research, Laparoscopic Surgery, Penile Cancer, Stress Urinary Incontinence and Adrenalectomy. The papers come from many different countries such as Italy, Brazil, USA, UK, Turkey, China, France, Iran, Republic of Korea, Argentina, India and Spain, and as usual the editor ́s comment highlights some papers. We decided to comment the paper about a very interesting topic: Robotic-Assisted Radical Prostatectomy (RARP). Doctor Neumaier and collegues from the FMUSP, Brazil performed on page 703 (1) an interesting study about the factors involved in urinary continence and sexual potency recovery after robotic-assisted radical prostatectomy (RARP). They studied 104 patients operated by two surgeons between 2008 and 2015, with a minimum 12 months follow-up. The patient features (age, body mass index, PSA, date of surgery and sexual function), tumor features (tumor stage, Gleason and surgical margins) and follow-up data (time to reach urinary continence and sexual potency) were collected at 1, 3, 6 and 12 month and every 6 months thereafter. Until the end of the study, only one patient was incontinent and 20.7% were impotent. The authors concluded that the age was a predictor of urinary and erectile function recovery in 12 months and the body mass index was significant factor for potency recovery. With the introduction of robotic surgery, some technical difficulties in laparoscopic surgery were lessened, due to, among other factors, the three-dimensional field of vision, hand tremor filtration and greater ergonomic freedom of movement of the surgeon (2-7). RARP in comparison with the open radical prostatectomy is associated with smaller positive surgical margins for pT2 tumors and better sexual function results during 12 months, and less impairment of urinary function during 12 months (8). Retrospective studies indicate that urinary control rates are better in younger patients, although there is conflicting data in the literature (9-12). This can be explained by the degeneration of the rhabdosphincter, which occurs with age. In this paper the authors had 16 patients with body mass index (BMI) ≥ 30 kg/m2 at the time of surgery and there was no statistical difference in recovery of urinary continence compared to patients with BMI < 30 kg/m2, but the average time to reach urinary continence was almost double for obese patients. The present paper also confirms that the age in an important factor to impotence recovery. We congratulate the authors for this very important contribution. Age and Body Mass Index: the most important factors of urinary and erectile function recovery after robotic assisted radical prostatectomy Vol. 45 (4): 653-654, July August, 2019
年龄和体重指数:机器人辅助根治性前列腺切除术后泌尿和勃起功能恢复的最重要因素
2019年7 - 8月的《国际巴西泌尿学杂志》(International Brazilian Journal of Urology)在不同领域发表了许多有趣的原创论文:不育症、膀胱增强术、膀胱癌、PCNL、前列腺癌、肾细胞癌、部分肾切除术、肾结石、夜间遗尿、基础研究、腹腔镜手术、阴茎癌、压力性尿失禁和肾上腺切除术。这些论文来自许多不同的国家,如意大利、巴西、美国、英国、土耳其、中国、法国、伊朗、韩国、阿根廷、印度和西班牙,像往常一样,编辑的评论突出了一些论文。我们决定评论一个非常有趣的话题:机器人辅助根治性前列腺切除术(RARP)。来自巴西FMUSP的Neumaier医生和他的同事在第703(1)页上进行了一项有趣的研究,研究涉及机器人辅助根治性前列腺切除术(RARP)后尿失禁和性能力恢复的因素。他们研究了2008年至2015年间由两名外科医生手术的104名患者,并进行了至少12个月的随访。患者特征(年龄、体重指数、PSA、手术日期、性功能)、肿瘤特征(肿瘤分期、Gleason、手术切缘)、随访资料(达到尿失禁时间、性能力)分别于1、3、6、12个月及以后每6个月收集一次。直到研究结束,只有1名患者失禁,20.7%的患者阳痿。作者得出结论,年龄是12个月内泌尿和勃起功能恢复的一个预测因素,体重指数是性功能恢复的重要因素。随着机器人手术的引入,腹腔镜手术的一些技术难题得到了缓解,其中包括三维视野、手部震颤过滤和外科医生更大的符合人体工程学的行动自由等因素(2-7)。RARP与开放式根治性前列腺切除术相比,pT2肿瘤的手术阳性切界更小,12个月内的性功能结果更好,12个月内的尿功能损害更小(8)。回顾性研究表明,年轻患者的尿控制率更好,尽管文献中存在矛盾的数据(9-12)。这可以用横纹肌变性来解释,这种变性随着年龄的增长而发生。本文选取16例手术时体重指数(BMI)≥30 kg/m2的患者,与BMI < 30 kg/m2的患者相比,尿失禁的恢复无统计学差异,但肥胖患者达到尿失禁的平均时间几乎是肥胖患者的两倍。本文还证实,年龄是阳痿恢复的重要因素。我们祝贺作者的这一非常重要的贡献。机器人辅助根治性前列腺切除术后尿功能和勃起功能恢复的最重要因素:年龄和体重指数[j] .中国医学工程杂志,45 (4):653-654,2019
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