Cryptococcal Meningitis, A Rare Opportunistic Infection In An HIV Infected Nigerian Boy: A Case Report

A. Abdulkarim, O. Katibi, Ss Mohammed, H. Ekundayo, A. Fadeyi, A. Alarape
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引用次数: 1

Abstract

Cryptococcal meningitis (CM) is an uncommon opportunistic infection in HIV infected children. Few childhood cases have been reported in literature. This is the second case report in a Nigerian child and the first at our hospital. A 13 year old boy presented with fever, cough, neck pain, convulsions and altered sensorium. He was assessed clinically and results of laboratory investigations supported a diagnosis of CM. He was diagnosed HIV positive at the same time with a history of blood transfusions in a private hospital. Unfortunately, appropriate intravenous anti-fungal to be used for treatment were not available and child died within a week of diagnosis. The pandemicity of HIV requires that a high index of suspicion be maintained to detect invasive fungal infections like CM. Efforts should also be made to ensure availability of appropriate antifungal, such as amphotericin B, for prompt treatment of affected persons. There is similarly the need to reinforce the campaign on screening of blood and blood products to prevent HIV transmission. Key words: Cryptococcal meningitis, Nigerian child, HIV/AIDS
隐球菌性脑膜炎,一种罕见的机会性感染在一个感染HIV的尼日利亚男孩:一个病例报告
隐球菌性脑膜炎(CM)是HIV感染儿童中一种罕见的机会性感染。文献中很少报道儿童病例。这是尼日利亚儿童报告的第二例病例,也是我们医院的第一例。一个13岁的男孩表现为发烧,咳嗽,颈部疼痛,抽搐和感觉改变。他进行了临床评估,实验室调查结果支持CM的诊断。与此同时,他被诊断为艾滋病毒阳性,并在一家私立医院接受过输血。不幸的是,没有适当的静脉抗真菌药物用于治疗,儿童在诊断后一周内死亡。艾滋病毒的流行要求保持高度的怀疑指数,以发现像CM这样的侵袭性真菌感染。还应努力确保提供适当的抗真菌药物,如两性霉素B,以便及时治疗受影响的人。同样,需要加强血液和血液制品筛查运动,以预防艾滋病毒传播。关键词:隐球菌性脑膜炎,尼日利亚儿童,HIV/AIDS
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