Stereotactic radiotherapy with simultaneous integrated protection planning technique for synovial sarcoma with stomach abutment: A case report of a complete response

Tumor discovery Pub Date : 2023-05-10 DOI:10.36922/td.356
M. Bonù, Eneida Mataj, Jacopo Balduzzi, M. Cefaratti, G. Pedersoli, Gianluca Cossali, L. Triggiani, D. Tomasini, M. Buglione, S. Magrini
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引用次数: 1

Abstract

Here, we report the clinical case of a 44-year-old lady, affected by synovial sarcoma (SS) of the mediastinum which was treated in 2014, and relapsed in the upper abdomen in 2020. SS is a relatively radioresistant disease, radiotherapy (RT) is routinely reserved for the neoadjuvant/adjuvant or palliative context. In our scenario, stereotactic RT consisting in 45Gy in 6 fractions was proposed to manage the upper abdominal relapse. Exploiting simultaneous integrated protection, a deliberated reduction in the dose prescription in area of planning target volume overlapped with stomach was achieved, obtaining reasonable dosimetric goals. Acute toxicity in the patient was acceptable, and she did not experience late toxicity and was still free from disease, as noted in last follow-up, 15 months after treatment.
立体定向放疗联合综合保护计划技术治疗胃基滑膜肉瘤1例完全缓解
在这里,我们报告了一名44岁的女性,2014年接受治疗的纵隔滑膜肉瘤(SS)于2020年在上腹部复发。SS是一种相对耐辐射的疾病,放疗(RT)通常用于新辅助/辅助或姑息治疗。在我们的方案中,立体定向放疗包括45Gy,分为6个部分,被建议用于治疗上腹部复发。利用同步综合防护,实现了计划靶体积与胃重叠区域剂量处方的刻意减少,获得了合理的剂量学目标。患者的急性毒性是可以接受的,并且在治疗后15个月的最后一次随访中,她没有出现晚期毒性,仍然没有疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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