Erythrina Alkaloids: An Updated Review with Neurological Perspective.

A. Salem, Nada M. Mostafa, Eman Al‐Sayed, A. Singab
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引用次数: 0

Abstract

Erythrina is a genus comprising several plant species that are distributed in tropical and subtropical regions. This genus is a source of many phytoconstituents, with alkaloids and flavonoids as the main bioactive components. Erythrina alkaloids are characterized by a unique nucleus. One hundred ninety-eight alkaloids were isolated from Erythrina plants till early 2023. Recently, an increase in the number of isolated dimeric alkaloids has been witnessed. Erythrina plants have been used in the management of different conditions such as oxidative stress and diseases like cancer, inflammation, viral diseases, malaria, and diabetes, with the alkaloids showing a good potential against certain neurological disorders like anxiety, epilepsy, and Alzheimer’s disease. All data on Erythrina alkaloids were collected from Google Scholar, ScienceDirect, SCOPUS, and SciFinder. For compounds isolated from multiple Erythrina species, the plant source was traced only from 2008 till 2023. The reported anxiolytic, anti-convulsant, and anti-Alzheimer’s activities of Erythrina plant metabolites were traced from 2002 till 2023.
赤藓生物碱:从神经学角度的最新综述。
赤藓属是一个由几种植物组成的属,分布在热带和亚热带地区。该属是许多植物成分的来源,以生物碱和类黄酮为主要的生物活性成分。赤藓生物碱具有独特的细胞核。截至2023年初,共从赤藓属植物中分离到198种生物碱。近年来,分离的二聚体生物碱的数量有所增加。赤藓属植物已被用于治疗不同的疾病,如氧化应激和癌症、炎症、病毒性疾病、疟疾和糖尿病等疾病,其生物碱对某些神经系统疾病,如焦虑、癫痫和阿尔茨海默病,显示出良好的潜力。Erythrina生物碱的所有数据均来自Google Scholar、ScienceDirect、SCOPUS和SciFinder。对于从多个赤藓属植物中分离的化合物,其植物来源仅从2008年到2023年进行了追踪。从2002年到2023年,报道了赤藓属植物代谢产物的抗焦虑、抗惊厥和抗阿尔茨海默病活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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