Investigation of Vitamins, Glutathione and Stress Biomarkers in Blood Serum of Patients with Breast Cancer

Abstract

Breast cancer is a genetic disease caused by the accumulation of mutations in neoplastic cells and is responsible for the highest morbidity and mortality. In this study, blood serum samples from 45 breast cancer patient and 32 healty individual (control group) were used. The amounts of vitamins (A, E, β-carotene, C, B1, B2, B3, B5, B6, B9 and B12), glutathione (GSH, GSSG) stress biomarkers (4-HNE, MDA) were determined by HPLC. A significant difference was found between the breast cancer patients and the control group in terms of age and body mass index (BMI) (p