Correlation of Ankle-Brachial Index and Ultrasound Findings on Dorsalis Pedis Artery and Posterior Tibial Artery in Patients with Diabetic Foot Ulcer

D. Pratama, Mulawardi Mulawardi, Patrianef Darwis
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Abstract

Introduction: In patients with diabetic foot ulcers, atherosclerosis, and endothelial dysfunction can worsen the patient’s vascular condition. Atherosclerosis is one of which is assessed by the ankle-brachial index (ABI). The occurrence of endothelial dysfunction can be identified indirectly from the examination of flow-mediated dilatation (FMD) via doppler ultrasound. This study was conducted to determine whether there is a correlation between the ankle-brachial index examination with ultrasound examinations of the dorsalis pedis artery and posterior tibial arteries in diabetic foot sufferers. Method: The study design was a cross-sectional prospective conducted on 11th November – 15th December 2014 at Cipto Mangungkusumo National Hospital, Fatmawati National Hospital, and Tangerang Hospital. The inclusion criteria used were diabetics and allow for ABI examination and ultrasonography. Patients who did not have a precise diagnosis and had undergone a major amputation of the leg examined were excluded from the study. Results: From the Spearman non-parametric correlation analysis test results obtained significant results on the correlation between ABI and posterior tibial artery volume flow (VF) (p=0.021). In contrast, insignificant results were obtained on the correlation between peak systolic velocity (PSV) dorsalis pedis artery with ABI (p=0.561), as well as an insignificant correlation between VF of dorsalis pedis artery with ABI (p=0.143), as well as insignificant correlation on PSV of posterior tibial artery with ABI (p=0.231) The results of Spearman’s non-parametric correlation analysis test results obtained significant results on the correlation between ABI and ABI spectral picture (p=0,000) in the diabetic foot. Conclusion: There was a significant correlation between the posterior tibial artery VF with ABI and the Doppler ultrasound spectral picture with ABI. Keywords: ultrasound doppler, ankle-brachial index, diabetic foot ulcer, dorsalis pedis artery, popliteal artery
糖尿病足溃疡患者踝肱指数与足背动脉、胫后动脉超声表现的相关性
在糖尿病足溃疡患者中,动脉粥样硬化和内皮功能障碍可使患者的血管状况恶化。动脉粥样硬化是其中之一,通过踝肱指数(ABI)来评估。内皮功能障碍的发生可以通过多普勒超声检查血流介导扩张(FMD)间接确定。本研究旨在探讨糖尿病足患者踝肱指数检查与足背动脉、胫后动脉超声检查是否存在相关性。方法:研究设计为横断面前瞻性研究,于2014年11月11日至12月15日在Cipto Mangungkusumo国立医院、Fatmawati国立医院和Tangerang医院进行。纳入标准为糖尿病患者,并允许ABI检查和超声检查。没有准确诊断并接受过腿部主要截肢检查的患者被排除在研究之外。结果:Spearman非参数相关分析检验结果显示ABI与胫骨后动脉容积流量(VF)的相关性显著(p=0.021)。足背动脉收缩峰值速度(PSV)与ABI的相关性不显著(p=0.561),足背动脉VF与ABI的相关性不显著(p=0.143)。胫骨后动脉PSV与ABI的相关性不显著(p=0.231)。Spearman非参数相关分析检验结果显示,糖尿病足ABI与ABI谱图的相关性显著(p= 0000)。结论:胫骨后动脉VF与ABI及多普勒超声频谱图有显著相关性。关键词:超声多普勒,踝肱指数,糖尿病足溃疡,足背动脉,腘动脉
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