BMK Blood Test Result as Evaluation of Bisphosphonates Used for the Treatment of Osteoporosis

Abstract

ARCH Women Health Care, Volume 4(1): 1–3, 2021 There has been long use of Bisphosphonates for bone antiresorption; for example, Alendronate 10 mg: 1 tablet/day Alendronate 70 mg: 1 tablet/week Risedronate 5 mg: 1 tablet/day Risedronate 35 mg: 1 tablet/week Risedronate 150 mg: 1 tablet/month Ibandronate 150 mg: 1 tablet/month However, effectiveness of the recommended dosage and appropriate length of time have never been evaluated. After blood test for Biological Bone Marker, studies have been gathered for more than 10 years or since 2005-2017, and surprisingly, remarkable results have been found out. First of all, BMK blood test must be correct throughout its process, for reliable and accurate results [1]. 1. No food is allowed for patients from 8 pm to 8 am (12 hrs) 2. Blood sample is taken between 8 am to 9 am only (normal values specified by Prof. Dr. Narong B) 3. Blood Test by the Laboratory needs to be done immediately as result value varies by time. 4. Solution used for running the BMK blood test must be calibrated every morning. This report covers evaluation on bone resorting value which is CTx or Beta Cross Laps only. Normal value specified by Prof. Dr. Narong B. is 0.31 for female [2]. If CTx or Beta Cross laps as measured = 0.31 for female, there will be 100% bone resorption, as normal, for female. If CTx is more than 100% bone resorption is faster or higher than normal. If CTx is less than 100%, bone resorption is slower or lesser than normal. Example CTx value of a patient = 0.45 CTx 0.31 = 100% Review Article BMK Blood Test Result as Evaluation of Bisphosphonates Used for the Treatment of Osteoporosis Emeritus Sek Aksaranugraha* Director, Thai Red Cross Rehabilitation Center, Samut Prakarn, Thailand *Corresponding author: Emeritus Sek Aksaranugraha, Director, Thai Red Cross Rehabilitation Center, Samut Prakarn, Thailand