Radical Metal-Free Borylation of Aryl Iodides

IF 2.2 4区化学 Q2 CHEMISTRY, ORGANIC

Synthesis-Stuttgart Pub Date : 2017-05-29 DOI:10.1055/s-0036-1588431

Sandra Pinet, V. Liautard, Mégane Debiais, Mathieu Pucheault

引用次数: 18

Abstract

Abstract A simple metal-free borylation of aryl iodides mediated by a fluoride sp2–sp3 diboron adduct is described. The reaction conditions are compatible with various functional groups. Electronic effects of substituents do not affect the borylation while steric hindrance does. The reaction proceeds via a radical mechanism in which pyridine serves to stabilize the boryl radicals, generated in situ.

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芳基碘化物的自由基无金属硼化

摘要描述了氟化sp2-sp3二硼加合物介导的芳基碘化物的简单无金属硼化反应。反应条件与各种官能团相适应。取代基的电子效应不影响硼化反应，而位阻影响硼化反应。反应通过一种自由基机制进行，其中吡啶起到稳定原位生成的硼基自由基的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Synthesis-Stuttgart 化学-有机化学

CiteScore

4.50

自引率

7.70%

发文量

435

审稿时长

1 months

期刊介绍： SYNTHESIS is an international full-paper journal devoted to the advancement of the science of chemical synthesis. It covers all fields of organic chemistry involving synthesis, including catalysis, organometallic, medicinal, biological, and photochemistry, but also related disciplines. SYNTHESIS provides dependable research results with detailed and reliable experimental procedures and full characterization of all important new products as well as scientific primary data.