{"title":"Use-fullness of dynamic contrast-enhanced MR imaging and diffusion weighted MR imaging for differentiation of benign and malignant parotid tumors","authors":"S. Zheng, Zf Xu, Xh Wu, A. Pan","doi":"10.36879/jcmi.18.000101","DOIUrl":null,"url":null,"abstract":"Objectives: To evaluate the usefullness of dynamic contrast-enhanced MR Imaging (DCE-MRI) and diffusion weighted imaging (DWI) for differentiating benign from malignant\nparotid tumors.\nMethods: Prospectively,DCE-MRI and DWI were performed in 112 patients, with 148 confirmed parotid masses. The differential optimal thresholds were determined.\nResults: WConsidering tumors with time-intensity curve (TIC) Type C as malignant, sensitivity, specificity, accuracy were 95%, 76%, 79%, respectively. Considering ADC threshold\nvalues 0.709×10-3mm2\n/s<ADC<0.948×10-3mm2\n/s as malignant, sensitivity, specificity, accuracy were 75%, 78%, 78%, respectively. Considering TIC Type C and ADC values\n0.709×10-3mm2\n/s<ADC<0.948×10-3mm2\n/s as malignant, sensitivity, specificity, accuracy were 75%, 91%, 89%, respectively. With threshold Kep<1.118 min-1 and Ve\n>0.315 between\nWarthin and malignant tumors, threshold Kep>0.555 min-1 and Ve\n<0.605 between pleomorphic adenomas and malignant tumors, sensitivity, specificity, accuracy for malignancy\nwere 70% vs 90%, 96% vs 74%, 92% vs 80%, respectively.\nConclusion: DCE-MRI and DWI provide more information in differentiating benign from malignant parotid tumors.","PeriodicalId":91401,"journal":{"name":"SM journal of clinical and medical imaging","volume":"76 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SM journal of clinical and medical imaging","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36879/jcmi.18.000101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Objectives: To evaluate the usefullness of dynamic contrast-enhanced MR Imaging (DCE-MRI) and diffusion weighted imaging (DWI) for differentiating benign from malignant
parotid tumors.
Methods: Prospectively,DCE-MRI and DWI were performed in 112 patients, with 148 confirmed parotid masses. The differential optimal thresholds were determined.
Results: WConsidering tumors with time-intensity curve (TIC) Type C as malignant, sensitivity, specificity, accuracy were 95%, 76%, 79%, respectively. Considering ADC threshold
values 0.709×10-3mm2
/s0.315 between
Warthin and malignant tumors, threshold Kep>0.555 min-1 and Ve
<0.605 between pleomorphic adenomas and malignant tumors, sensitivity, specificity, accuracy for malignancy
were 70% vs 90%, 96% vs 74%, 92% vs 80%, respectively.
Conclusion: DCE-MRI and DWI provide more information in differentiating benign from malignant parotid tumors.