Concept of Neutron Source Creation for Nuclear Medicine on the Basis of Linear Electron Accelerator

V.Y. Kasilov, S. Gokov, S. Kalenik, S. Kochetov, Leonid Saliy, V. Tsyats'ko, Evgen Tsyats'ko, O. Shopen
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引用次数: 1

Abstract

We review the current status of the development of sources of epithermal neutrons sources based on reactors and accelerators for boron neutron capture therapy (BNCT), a promising method of malignant tumor treatment. The scheme is proposed of the source prototype for the production of thermal and epithermal neutrons using the delayed neutrons generated with help of linear electron accelerator at the target containing the fissile material. The results of an experiment are presented in which the half-life curves of radioactive nuclei formed during fission and emitting delayed neutrons are measured. It is shown that an activated target containing fissile material is a compact small-sized source of delayed neutrons. It can be delivered to the shaper, where, using a moderator, an absorber, and a collimator, neutrons of thermal or epithermal energies are formed over a certain period of time, after which this target is sent to the activator, and another target comes in its place. Thus, a pulsed neutron flux is formed. Such a neutron beam can be used in nuclear medicine, in particular, in neutron capture therapy in the treatment of cancer. An important task in the implementation of neutron capture therapy, when irradiating patients, is to control both the intensity and the energy spectrum of the neutron flux. To solve this problem, an earlier developed activation-type neutron ball spectrometer can be used, which will allow optimization of various parameters of the shaper, collimator and filters in order to obtain the most powerful neutron fluxes.
基于直线电子加速器的核医学中子源创建构想
本文综述了硼中子俘获治疗(BNCT)的超热中子源的研究现状,硼中子俘获治疗是一种很有前途的恶性肿瘤治疗方法。提出了利用线性电子加速器产生的延迟中子在含有裂变物质的靶上产生热中子和超热中子的源原型方案。本文介绍了在裂变过程中形成的放射性原子核发射迟发中子的半衰期曲线的测量结果。结果表明,含有可裂变物质的活化靶是一个紧凑的小尺度延迟中子源。它可以被送到成形器,在那里,使用慢化剂、吸收剂和准直器,在一定的时间内形成热或超热能的中子,之后这个目标被送到激活剂,另一个目标来代替它。这样,就形成了脉冲中子通量。这种中子束可用于核医学,特别是用于治疗癌症的中子俘获疗法。在实施中子俘获治疗时,一个重要的任务是控制中子通量的强度和能谱。为了解决这个问题,可以使用较早开发的活化型中子球谱仪,它可以优化整形器、准直器和滤波器的各种参数,以获得最强大的中子通量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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